Better Edge : A Northwestern Medicine Podcast For Physicians

This Better Edge podcast episode features Robin L. Cohen, MD, Michelle Armour, MS, CCC-SLP, and Shamun Mohammed, MS, CCC-SLP, as they discuss the rehabilitation of a 77-year-old stroke patient with severe fluent aphasia, auditory comprehension challenges and apraxia. They highlight how interdisciplinary collaboration, strong family involvement and the Northwestern Medicine Aphasia Program at Marianjoy Rehabilitation Hospital led to significant functional gains and renewed independence.

In this episode of Better Edge, Akhil Narang, MD, associate professor of Cardiology at Northwestern Medicine, examines the phase 3 ENHANCE trial, which evaluates a novel syringe-mounted surfactant device designed to generate uniform microbubbles and reduce variability in saline contrast echocardiography. By improving right-heart opacification and the fidelity of right-to-left shunt detection, the device aims to improve diagnostic accuracy and reduce rates of non-diagnostic and repeat studies. Rooted in Bluhm Cardiovascular Institute’s commitment to advancing translational imaging, this trial may improve both workflow efficiency and patient care.

Prostate MRI is changing how clinicians decide when a biopsy is needed and how sampling is targeted to better detect clinically significant prostate cancer. In this episode of Better Edge, Hiten Patel, MD, discusses MRI‑informed risk stratification, including the use of an MRI‑based risk calculator, and how MRI‑targeted biopsy can reduce missed high‑grade disease. The episode also highlights how PSA density informs decision‑making after a negative MRI and how to manage discordant targeted and systematic biopsy results. Dr. Patel reviews lesion characteristics, like size and suspicion score, in the context of follow‑up and treatment intensity, along with emerging tools like PSMA PET and AI that may further refine detection and biopsy targeting.

In this episode of Better Edge, Baljash S. Cheema, MD, assistant professor of Cardiology at Northwestern Medicine, explores the integration of FDA-approved digital health technologies in cardiovascular care, focusing on a photoplethysmography-based algorithm for remote AFib detection and monitoring. Dr. Cheema discusses the clinical validation of this smartphone-enabled tool and its advantages over traditional wearables. He also highlights its implications for patient empowerment, stroke prevention and the evolving landscape of AI-driven diagnostics.

Oncologist George Georges, MD, moderates a discussion with Christine Hsieh, MD, rheumatologist, and Arjun Seth, MD, neurologist, on advancing care for inflammatory myopathies. The panel introduces the Northwestern Medicine Myositis Clinic, a one-stop model that simplifies diagnostics and connects patients to clinical trials. They review current treatment strategies — steroids, IVIg, steroid-sparing agents, rituximab, and JAK inhibitors — along with approaches for refractory disease. The panel also explores cellular therapies, including CAR-T cell trials.

In this episode of Parts and Labor, Angela Chaudhari, MD, hosts a panel of experts from Northwestern Medicine’s Division of Gynecologic Oncology to discuss the groundbreaking research and clinical trials shaping the future of gynecologic cancer care. The panel explores innovations in immunotherapy, investigator-initiated trials, survivorship and symptom science, while highlighting efforts to expand access and diversity in clinical research across Chicago and the surrounding suburbs.This episode’s panel of guests includes:• Emma L. Barber, MD, John and Ruth Brewer Professor of Gynecology and Cancer Research, Division Chief of Gynecologic Oncology and Director of Robotic Surgery• Daniela E. Matei, MD, Diana, Princess of Wales Professor of Cancer Research and Chief of Reproductive Science in the Departments of Obstetrics and Gynecology and Hematology and Oncology• Dario R. Roque, MD, Associate Professor of Gynecologic Oncology and Fellowship Program Director• Emily M. Hinchcliff, MD, Assistant Professor of Gynec

In this episode of Better Edge, Chandrika Shankar, MD, explores the dynamic intersection of mental health and law. Learn how forensic psychiatrists assess competency, navigate ethical dilemmas and balance risk assessment tools with clinical judgment. Dr. Shankar also shares insights on telepsychiatry, AI-assisted evaluations and the core skills needed to succeed in this evolving field.

In this episode of Better Edge, a Northwestern Medicine Ophthalmology panel including Paul Bryar, MD, Rukhsana G. Mirza, MD, and moderator Angelo P. Tanna, MD, discusses practical applications of artificial intelligence in eye care. Topics include point‑of‑care diabetic retinopathy screening with immediate results, oculomics and multimodal imaging, and collaborations using AI to identify biomarkers such as retinal ischemic perivascular lesions (RIPLs). The panel also reviews early experience with large language model triage and MyChart responses, EMR‑based risk scoring that incorporates social drivers of health and workflow optimization.

Edward M. Schaeffer, MD, PhD, moderates a thoughtful conversation with two former Northwestern Urology residents, Richard Matulewicz, MD, MSCI, MS, urologic surgeon at Memorial Sloan Kettering Cancer Center, and Neema Navai, MD, MHCM, professor and chair of the department of urology and special advisor to the chief physician executive for care development at MD Anderson Cancer Center. Together, they share insights from their professional journeys, explore the evolving landscape of urologic care and discuss how their experiences have shaped their career paths and approach to patient care.

In this episode of Parts and Labor, Angela Chaudhari, MD, hosts a panel of experts from Northwestern Medicine’s Division of Gynecologic Oncology to explore the innovative role of robotic surgery in cancer care. The discussion highlights how robotic technology is improving outcomes for patients with gynecologic cancers through minimally invasive techniques, enhanced precision and interdisciplinary collaboration.The panel covers advancements in robotic systems, patient populations who benefit most from this approach, including those with high BMI, complex surgical histories, and fertility concerns, as well as the future of surgical innovation at Northwestern Medicine.This episode’s panel of guests includes:• Emma L. Barber, MD, John and Ruth Brewer Professor of Gynecology and Cancer Research, Division Chief of Gynecologic Oncology and Director of Robotic Surgery.• Dario R. Roque, MD, Associate Professor of Gynecologic Oncology and Fellowship Program Director.• Jenna Z. Marcus, MD, Associate Professor of Gynecol

In this episode of Better Edge, a Northwestern Medicine Neurology panel including Niccolo Mencacci, MD, PhD, Sarah Brooker, MD, PhD, and Elizabeth Gerard, MD, discuss their groundbreaking research surrounding the NUS1 gene and its impact on neurological disorders.Their recently published research, The Spectrum of Neurologic Phenotypes Associated With NUS1 Pathogenic Variants: A Comprehensive Case Series, covers a comprehensive case series of 41 patients with pathogenic variants in the NUS1 gene, highlighting a spectrum of neurological phenotypes that include developmental delays, epilepsy, and various movement disorders. Notably, the study emphasizes the lack of genotype-phenotype correlations, suggesting the influence of additional genetic and environmental factors on clinical presentations.

In this episode of Better Edge, Edgar Woznica, MD, explores the clinical challenges of diagnosing and treating patients with four or more co-occurring psychiatric conditions, including substance use disorders. He shares strategies for distinguishing primary versus substance-induced symptoms, emphasizes the importance of collaborative care and offers guidance for teaching diagnostic clarity to trainees. The episode also highlights the value of embracing diagnostic uncertainty and measuring success through functional outcomes.Clinical impact: This conversation provides practical tools for managing diagnostic complexity and reinforces the importance of integrated, patient-centered care in high-acuity psychiatric cases.

In this episode of Better Edge, Sean W. P. Koppe, MD, moderates a panel of Northwestern Medicine hepatologists as they discuss recent scientific updates from the American Association for the Study of Liver Diseases (AASLD) annual meeting held in November 2025. The conversation addresses key updates in the management of patients with cirrhosis, MASLD, HCC, alcohol liver disease, cholestatic liver diseases and autoimmune hepatitis that were presented at the meeting.

A panel of Northwestern Medicine ophthalmologists, including Robert Feder, MD, Liza Cohen, MD, and Timothy Janetos, MD, share key highlights and clinical implications from the 2025 AAO Annual Meeting focusing on cornea and external disease, orbital and oculoplastic surgery, and uveitis — including cases associated with cataract.

In this episode of Better Edge, Quentin R. Youmans, MD, assistant professor of Cardiology at Northwestern Medicine Bluhm Cardiovascular Institute, discusses the recent joint scientific statement from the Heart Failure Society of America (HFSA) and the American Society of Preventive Cardiology (ASPC) published in the Journal of Cardiac Failure. This statement explores the integration of multidisciplinary care models in heart failure management, focusing on proactive strategies for early detection and prevention. It also emphasizes the importance of lifestyle modifications, social determinants of health and a shift in language from "failure" to "function" for enhancing patient engagement. Additionally, the research investigates the role of emerging technologies, such as wearables and AI, in revolutionizing care and proposes a cohesive framework that promotes cardiovascular, kidney and metabolic health to reduce heart failure incidence.

Danny Bega, MD, of Northwestern Medicine Neurology, joins Will Meador, MD, to discuss a major breakthrough in Huntington’s disease — a gene therapy that has shown the first evidence of slowing disease progression. Dr. Bega talks about how the RESET-HD trial is reshaping treatment possibilities and what physicians should watch for as this therapy advances.

In part two of the Better Edge series on women in physiatry, Larissa Pavone, MD, and Mary Keen, MD, reflect on how the field has evolved — from training structures and technology to the growing presence of women in leadership. They discuss the increasing demands of the specialty, the impact of mentorship and the importance of visibility and support for women entering PM&R. Looking ahead, they share their excitement about the role of technology and expanded access to education in shaping the future of physiatry. The episode offers practical insights for women navigating the field today and encourages continued growth through collaboration and innovation.

In this episode of Better Edge, Brandon Hamm, MD, discusses an evidence-based approach to ketamine therapy, including patient selection, safety protocols and a newly expanded infusion suite. He compares ketamine with TMS and ECT, addresses common misconceptions and highlights training opportunities for residents. The episode also previews emerging treatments like vagus nerve stimulation.Clinical impact: This conversation underscores ketamine’s growing role as a safe, effective option within a comprehensive interventional psychiatry framework.

In this episode of Better Edge, Larissa Pavone, MD, and Mary Keen, MD, share their insights on the power of mentorship among women in physiatry. They reflect on their own mentor and mentee relationship, emphasizing how guidance, partnership and shared clinical experiences have shaped their careers and personal growth.They explore the challenges of balancing clinical demands with personal well-being and the importance of being present for patients and families. The episode highlights how mentorship can come from many sources and evolve over time. Both physicians offer practical advice for women seeking mentorship and underscore the importance of recognizing mentors across disciplines within the rehabilitation team.This is part one of a two-part series. Be sure to listen to part two where Dr. Pavone and Dr. Keen discuss the evolution of women in physiatry and the future of the field.

In this episode of Better Edge, Jennifer Miles-Thomas, MD, moderates a thoughtful conversation with Anthony Schaeffer, MD, discussing complicated urinary tract infections (cUTIs) and their management. Dr. Schaeffer, who contributed to the recent IDSA guidelines on cUTIs, emphasizes the need to understand underlying causes of recurrent infections rather than treating them as isolated events. The conversation explores critical topics such as antibiotic resistance, effective treatment strategies and the importance of early intervention in febrile cases.