Evolution Of Medicine Podcast

What if chronic disease, cognitive decline, and even trauma were not fixed conditions—but modifiable biological states? In this Functional Forum episode, James Maskell and Matt Wiggins bring together leading clinicians and researchers to explore the frontiers of precision and functional medicine. They discuss SUPAR, a powerful biomarker for systemic inflammation that could reshape early disease detection. The conversation then turns to a groundbreaking cognitive decline trial showing major improvements in patients treated with functional medicine protocols compared to standard care. The episode also explores the biology of loneliness and the "cell danger response," the reversibility of trauma through epigenetic mechanisms and psychedelic-assisted therapy, and emerging ideas about measuring masculinity as a clinical health indicator. Together, these insights point toward a future where chronic disease may be detected earlier, treated systemically, and in some cases reversed. - - - - - About the Guests: This ep