60-second Science

In this episode, host Rachel Feltman speaks with freelance science journalist Hannah Seo about a promising new development in male contraception: a hormone-free birth control pill that reversibly stops sperm production has just passed its first human safety trial. Seo explains how the drug works, what makes it different from hormone-based methods and where it stands in clinical development.   Recommended reading: First Hormone-Free Male Birth Control Pill Shown Safe in Early Human Trial Male Birth Control Is in Development, but Barriers Still Stand in the Way “Safety and Pharmacokinetics of the Non-Hormonal Male Contraceptive YCT-529,” by Nadja Mannowetz et al., in Communications Medicine, Vol. 5, Article No. 279. Published online July 22, 2025 Email us at [email protected] if you have any questions, comments or ideas for stories we should cover! Discover something new every day: subscribe to Scientific American and sign up for our daily newsletter. Science Quickly is produced by Rachel Fel